Anikó Borbás


Anikó Borbás, Ph.D., D.Sc.

Phone: +36-52-512-900 ext. 22475
Fax: +36-52-512-914
E-mail: aniko·borbas.aniko {AT} science·unideb·hu

Date and place of birth:

December 12, 1965, Jászapáti, Hungary

Current position:

Associate Professor, Head of Department


1984-1989M.Sc. in Chemistry, Lajos Kossuth University, Debrecen
1989-1992Research Scholarship from the Hungarian Academy of Sciences, supervisor Prof. András Lipták
1997Ph. D. dissertation: "Preparation and hydrogenolysis of dioxolane-type diphenylmethylene acetals. Synthesis of the immunodeterminant cell-wall trisaccharide of Mycobacterium leprae" supervisor Prof. András Lipták, grade "summa cum laude"
1998-2000Magyary Zoltán postdoctoral fellowship from the Hungarian Ministry of Culture and Education
2010Habilitation: Synthesis of biorelevant oligosaccharides and their analogues


Research fellowDepartment of Biochemistry, University of Debrecen (1989-1996)
Senior research fellow,Research Group for Carbohydrates of the Hungarian Academy of Sciences, University of Debrecen (1997-2010)
Associate professorDepartment of Pharmaceutical Chemistry, University of Debrecen (2011-)
Head of DepartmentDepartment of Pharmaceutical Chemistry, University of Debrecen (2012-)

Publications: 53 publications in peer-reviewed journals, 1 book contribution.

Invited lectures:

2008, 3rd ERA-Chemistry Flash Conference, 09?13 March 2008, Killarney, Ireland
2008, 4th Central European Conference: Chemistry towards Biology, 2008. 09. 08-11., Dobogókö, Hungary
2011, Conference in Organic and Biomolecular Chemistry, May 26-29, 2011, Goslar, Germany

Research interest:

Introduction of sulfonic acid moieties to saccharide molecules. Synthesis of heparinoid mimetics of anticoagulant activity. Synthesis of oligosaccharides against HIV and influenza infections. Acetal protecting groups of carbohydrates. Synthetic modification of glycopeptide antibiotics. Photoinduced hydrothiolation of unsaturated carbohydrates.

Ten most relevant publications:
(Download full list of publications here)

  1. A. Borbás, G. Szabovik, Zs. Antal, K. Fehér, M. Csávás, L. Szilágyi, P. Herczegh, A. Lipták: Sulfonic acid analogues of the sialyl Lewis X tetrasaccharide. Tetrahedron: Asymmetry, 11 (2000) 549-566.
  2. A. Lipták, A. Borbás, L. Jánossy, L. Szilágyi: Preparation of (2-naphthyl)methylene acetals of glycosides and their hydrogenolytic transformation into 2-naphthylmethyl (NAP) ethers. Tetrahedron Lett., 41 (2000) 4949-4953.
  3. M. Csávás, A. Borbás, L. Szilágyi, A. Lipták: Successful combination of (methoxydimethyl)methyl (MIP) and (2-naphthyl)methyl (NAP) ethers for the synthesis of arabinogalactan-type oligosaccharides. Synlett, (2002) 887-890.
  4. M. Herczeg, L. Lázár, A. Borbás, A. Lipták, S. Antus: Toward synthesis of the isosteric sulfonate analogues of the AT-III binding domain of heparin. Org. Lett., 11 (2009) 2619-2622.
  5. M. Herczeg, L. Lázár, Zs. Bereczky, K. E. Kövér, I. Timári, J. Kappelmayer, A. Lipták, S. Antus, A. Borbás: Synthesis and anticoagulant activity of bioisosteric sulfonic acid analogues of the antithrombin-binding pentasaccharide domain of heparin. Chem. Eur. J. 18 (2012) 10643-10652.
  6. L. Lázár, E. Mezö, M. Herczeg, A. Lipták, S. Antus, A. Borbás: Synthesis of the non-reducing end trisaccharide of the antithrombin-binding domain of heparin and its bioisosteric sulfonic acid analogues. Tetrahedron, 68 (2012) 7386-7399
  7. L Lázár, M. Csávás, M. Herczeg, P. Herczegh, A. Borbás: Synthesis of S-linked glycoconjugates and S-disaccharides by thiol&;ndash;ene coupling reaction of enoses Org. Lett., 14 (2012) 4650-4653.
  8. A. Sipos, Zs. Török, E. R?th, A. Kiss-Szikszai, Gy. Batta, I. Bereczki, Z. Fejes, A. Borbás, E. Ostorházi, F. Rozgonyi, L. Naesens, P. Herczegh: Synthesis of isoindole and benzoisoindole derivatives of teicoplanin pseudoaglycon with remarkable antibacterial and antiviral activities. Bioorg. Med. Chem Lett., 22 (2012) 7092-7096.
  9. M. Herczeg, E. Mezö, L. Lázár, A. Fekete, K. E. Kövér, S. Antus, A. Borbás: Novel syntheses of Idraparinux, the anticoagulant pentasaccharide with indirect selective factor Xa inhibitory activity. Tetrahedron, 69 (2013) 3149-3158.
  10. M. Csávás, M. Herczeg, A. Borbás: Synthesis of S-linked N-acetylneuraminic acid derivatives via photoinduced thiol-ene and thiol-yne couplings. Synlett, 24 (2013) 719-722.